Annihilate (v) : to destroy (someone or something) completely
Definition from Merriam-Webster (http://www.merriam-webster.com/dictionary/annihilated)
From The Shawl by Cynthia Ozick (paragraph 5)
They were in a place without pity, all pity was annihilated in Rosa, she looked at Stella’s bones without pity.
There were no pity in the place (in the situation). Rosa thinks all pity was completely destroyed because it no longer exist in the place.