Eukaryotic gene expressionUnlike prokaryotic genes, expression of genes in eukaryotic cells have complex systems of transcription factors that act on promoters to recruit RNA polymerases. Additionally, enhancer elements may reside many kilobase upstream of the promoter. These enhancers strengthen the transcription of the gene. In this case, transcription activator proteins or trans-activators augment the promoter activity. Mediator proteins (coactivators) form a multiprotein complex with the activators to recruit RNA polymerase to the promoter.
What kinds of decisions are made for stem cells to differentiate into different cell types? What types of regulation occur during this process?
- Transcription Simulation (MIT License)
- Transcription (CC-BY-NC-ND Cold Spring Harbor Lab – DNA Learning Center)
- Translation (CC-BY-NC-ND Cold Spring Harbor Lab – DNA Learning Center)