| Week | Topic | Lab Exercise |
| 1 | Observational Errors | — |
| 2 | Summary Statistics | The Hubble Law |
| 3 | Probability Distribution Functions | — |
| 4 | Cumulative Distribution Functions | Radioactive Decay |
| 5 | Normal Distribution | — |
| 6 | Correlation and Covariance | Weighing the Earth |
| 7 | Sampling Distributions | — |
| 8 | Midterm | The HR Diagram |
| 9 | Estimation | — |
| 10 | Hypothesis Testing | Discovery of the Atomic Nucleus |
| 11 | Linear Least Squares | — |
| 12 | Regression | Discovery of the Higgs Boson |
| 13 | Liklihood | — |
| 14 | Bayes Theorem | Lab 7 |
| 15 | Final Exam | Oral Presentations |
